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Expert witness 'changed mind' over deaths, say Lucy Letby lawyers – BBC

Lucy Letby's lawyers have said they will be asking the Court of Appeal to immediately review all of her convictions because an expert witness "has now changed his mind on the cause of death of three babies".
The former nurse is serving 15 whole-life jail terms for murdering seven babies and trying to kill seven others while working as a neo-natal nurse at the Countess of Chester Hospital.
Her barrister Mark McDonald told a news conference in London that the lead prosecution expert, Dr Dewi Evans, had altered his view.
He said: "Remarkably, Dr Evans has now changed his mind on the cause of death of three of the babies: Baby C, Baby I and Baby P."
Letby was convicted in August 2023 and was refused permission to appeal against her convictions in May.
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SOFTSWISS kicks off Prime Network Jackpot with $1.05 million base prize – Yogonet International

iGaming solutions provider SOFTSWISS has invited operators to join the current Prime Network Jackpot, which began with an initial prize pool of over 1,000,000 euros ($1.05 million). The base amount is ten times larger than the starting pool of the first Prime Network Jackpot launched in October 2023.
Operators can join the current Prime Network Jackpot at any time before the drop. The prize pool will continue to grow as more participating casinos contribute to it. Ultimately, one lucky winner from a single casino will claim the grand prize of over 1,000,000 euro.
SOFTSWISS says that the Prime Network Jackpot is especially appealing due to its “collaborative” approach. A shared prize pool is formed across participating operators, increasing the jackpot’s appeal to players.
The SOFTSWISS Jackpot Aggregator, a player engagement management solution, launched the Prime Network Jackpot feature last year. Since its launch, the feature has attracted a growing number of operators, resulting in larger prize pools with every draw.
“It’s a very exciting milestone for us. Over the past year, the SOFTSWISS Jackpot Aggregator and its Prime Network Jackpot feature have evolved significantly. Beyond the hard work of our professional team, this success reflects the high interest in engagement tools within the market,” said Anhelina Stasiuk, Head of Business Line at SOFTSWISS Jackpot Aggregator
In iGaming, prize size matters. I’m proud that we’ve reached a level where we can offer the best solutions.”
Recently, the SOFTSWISS Jackpot Aggregator announced the improvement of its product by introducing the Multi-Prizes feature. This new functionality enables operators to split winnings among several players or groups, offering customizable distribution methods tailored to various engagement strategies. 
In other recent news, SOFTSWISS held its first SOFTSWISS Excellence Talks event at the company’s main office in Poznań, Poland. The new quarterly initiative is aimed at cultivating a local community of professionals and strengthening ties with educational institutions.
The opening event featured a keynote address by Andrey Starovoitov, Co-CEO of SOFTSWISS, who welcomed attendees, and a special appearance by Rubens Barrichello, Formula 1 legend and Non-Executive Director in Latin America at SOFTSWISS.

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What are the Powerball numbers for Monday, Dec. 16? Jackpot stands at $55 million – Courier Journal

Do you have your tickets? Monday’s Powerball lottery jackpot is worth an estimated $55 million with a cash option of $25.7 million.
Monday’s Powerball numbers will be drawn at around 11 p.m. ET.
Saturday’s Powerball numbers were 12-17-23-52-67 and Powerball 1. The Power Play was 2x.
No one won Saturday’s Powerball Jackpot.
The possible winning tickets and their cash prizes are as follows:
Drawings are every Monday, Wednesday, and Saturday at 10:59 p.m. ET.
Here is the list of recent Powerball jackpot wins, per powerball.com:

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Relationship Between SARS-CoV-2 Variants, Infection, and Ct Values – Physician's Weekly





Dec 16, 2024
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The following is a summary of “Estimating the effect of COVID-19 vaccination and prior infection on Ct values as a proxy of SARS-CoV-2 viral load,” published in the December 2024 issue of Infectious Disease by Andeweg et al. 
Researchers conducted a retrospective study to assess the effect of COVID-19 vaccination and prior infection status on RT-qPCR cycle threshold (Ct) values while considering the virus variant as a factor.  
They used Dutch SARS-CoV-2 community testing data (n = 4,09,925 samples) from March 8, 2021, to December 31, 2022. Separate univariable linear regressions were performed for each explanatory variable, including age, sex, testing date, variant of infection, time since symptom onset, and testing laboratory. Causal inference analysis was then conducted to evaluate the impact of prior infection and vaccination status on Ct values, applying inverse propensity score weighting to adjust for confounders.  
The results showed a negative correlation between age and Ct values. Modest differences in Ct values were observed across variants of infection, with Omicron variants showing lower Ct values (higher viral load) compared to earlier variants. The Ct values increased (indicating lower viral load) with prior infection. However, the effect of vaccination on Ct values was less significant.  
Investigators concluded the prior infection was associated with higher Ct values, suggesting a potential decrease in viral load and potentially lower transmissibility. 
Source: ijidonline.com/article/S1201-9712(24)00437-5/fulltext 

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