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Update 6:30 p.m.: Interstate 80 E has now completely reopened to traffic. The interstate on-ramps that had been previously closed are now reopened as well.
Update 6:05 p.m.: The overturned semi-truck has been righted and traffic has begun flowing as the roadway opens up. The expected delay is now 24 minutes, according to the Iowa DOT.
Update 5:40 p.m.: Eastbound traffic has stopped again. The Iowa DOT now reports a 50-minute expected delay on I-80 eastbound.
You can see the latest traffic updates here.
Update: 5:25 p.m.: Traffic has begun moving in one eastbound lane as crews continue to work on the semi still laying across the road. The Iowa DOT now reports an expected delay of 22 minutes on I-80 eastbound.
Update 4:40 p.m.: According to the Iowa State Patrol, the incident is a two-vehicle crash involving a semi and a Chevrolet Equinox. The semi is overturned and blocking the roadway, causing the interstate closure. Serious injuries have been reported.
The ramps from Interstate 35 S to I-80 E and Interstate 235 E to I-80 E have been closed to thru traffic.
WATCH: Roadside crews use a crane to lift an overturned semi-truck on Interstate 80 eastbound on Wednesday evening.
Previous reporting
Traffic on Interstate 80 eastbound just east of Des Moines is at a standstill as a rolled-over semi blocks all lanes of traffic.
According to the Iowa Department of Transportation, the crash is located between Interstate 235 and Exit 141 near Ankeny, causing a traffic delay of about 35 minutes as of 4:15 p.m. Wednesday.
Traffic in the westbound lanes of I-80 in the area is also slowed significantly, with the DOT reporting a nine-minute delay.
The Iowa State Patrol says it is working to get the roadway reopened.
RAW VIDEO: Semi rollover blocks I-80 traffic
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