Auteur/autrice : Eric Mawuli DJIRACKOR
Epic Games sets Unreal and Unreal Tournament free on Internet Archive – Polygon
Two classic first-person shooters preserved by fans
by Ian Walker
Unreal, the first-person shooter that introduced Unreal Engine to the world, and its multiplayer-focused follow-up Unreal Tournament have been preserved via the Internet Archive and are freely available for download with the blessing of developer Epic Games.
Old Unreal first shared the news with its longstanding community of diehard Unreal fans on October 29 and, more recently, released special installers that streamline the process of getting these decades-old games ready to play on modern Windows operating systems. Of course, getting online will take further finagling — neither game has had official servers since Epic shut them down on January 24, 2023 — but community servers are still plentiful.
“We can confirm that Unreal and Unreal Tournament are available on Archive.org and people are free to independently link to and play these versions,” an Epic spokesperson told Polygon.
Unreal debuted in 1998. Designed by Cliff Bleszinski, who would go on to games like Gears of War and LawBreakers, and programmed by Tim Sweeney, the now-billionaire founder and CEO of Epic Games, the first-person shooter was an almost immediate hit thanks to its detailed graphics and fast-paced gameplay. Unreal Tournament followed in 1999, shifting the focus to multiplayer arenas and leading to multiple sequels. A reboot of sorts was planned but never moved past a 2014 public pre-alpha that ended in 2017, due to Epic’s development priorities shifting to Fortnite. And we all know how that turned out.
Despite a complete disappearance from the zeitgeist, unfortunately helped along by Epic itself delisting the games from all online storefronts when the servers were taken down in 2023, the Unreal series is an iconic piece of video game history that’s worth preserving for future generations. And while dedicated fans will always be ready to step in and do the hard work to save these abandoned classics, it’s great to see a major corporation like Epic at the very least do nothing to stymie those efforts.
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Chávez, Spirituality and Celebration: A Conversation with Joel Suárez (Part II) – Venezuelanalysis.com
Joel Suárez is a long-time social activist and theologian who is part of the Martin Luther King Memorial Center in Cuba. This ecumenical organization promotes social participation and solidarity. In this interview, Suárez offers an intimate and thought-provoking perspective on Venezuelan former President Hugo Chávez’s spiritual trajectory. In Part I, Suárez talked about Chávez’s first encounter with Fidel Castro and drew interesting connections between Liberation Theology and Chávez’s way of doing politics. Here, in Part II, we continue the conversation on Chávez’s unique leadership style.
You recalled earlier a phone conversation you had with Chávez before a mass rally in the context of the 2006 World Social Forum in Caracas. I remember that meeting in the Poliedro, which was extraordinary, with thousands attending. Can you tell our readers about it?
That day was extraordinary indeed. The event began with a “mística” with the Benedictine friar Marcelo Barros organized by Brazil’s Landless Workers Movement, but what was most moving was that it was the first time “The Internationale” was sung at a public act with Chávez… Many of us teared up singing it. Our community was coming together!
Politics is harsh and sometimes leaves wounds – disruptions, tensions, frustrations. These arise within organizations and among militants. Chávez was always conscious of this, so his speeches often began with a very long, detailed, and even boring list of salutations to acknowledge everyone present. He wanted everyone to know that they too were being taken into account.
In my view, Chávez’s practice of opening with long salutations, in addition to healing wounds, had a pastoral basis. For him, no one was more important than any other person who was present, regardless of whether they were a president, an intellectual, or an activist.
In any case, after all the long greetings and salutations, Chávez’s speech in the context of the World Social Forum was deliberate, careful, engaging, and meaningful.
That was one key moment in Chávez’s trajectory, but let’s rewind four years to another moment that you consider very important. It was when Fidel Castro sent an key message to Chávez during the coup d’état on April 11, 2002. Could you talk about that moment?
The story has been told before, but it’s worth recalling. When Fidel saw what was happening in Caracas, he realized that Chávez had an ethically grounded and politically essential disposition to give his life, to sacrifice it.
That is why, as the coup unfolded, Fidel told him, “cuídate” [take care of yourself].
Some say that Fidel also told him: “Don’t be like Allende!”
That’s right. In doing so, Fidel wasn’t undervaluing the ultimate sacrifice; rather, he was thinking about its purpose. The principle of hope that had materialized in the revolutionary struggle required that Chávez be alive.
Fidel was able to hold Chávez back, although the Venezuelan president’s disposition to make the ultimate sacrifice as a gift for life would re-emerge later.
That would be at the end of his life. Can you talk about Chávez’s “calvary,” his last years when he frequently visited Cuba to treat his cancer?
When Chávez was in the hospital in La Habana [2012], he asked that my dad [Reverend Raúl Suárez] send him books about Liberation Theology and other texts relating to these themes.
It should be pointed out, however, that for Chávez, even if he identified as a Christian and a believer, his spirituality was an open one. He drew from many sources.
I do not want to be sacrilegious – I want to respect believers who may not share my particular vision of Chávez as a man of Christian faith – but I see his faith as anthropological. It was a faith in life itself.
Chávez was going to live his Golgotha, his calvary, and he knew he could face the cross. When this became clear he flew back [to Venezuela] to confess to his community, to his comrades, to his pueblo. That was a moment that we – those committed to the revolution – experienced collectively.
Indeed, there are historical moments that become foci of collective consciousness. The episode you refer to on December 8, 2012, when Chavez announced on national television that he might die, was certainly one of them.
On December 8, many of us also experienced the mystery of God. For me, the great mystery in Jesus Christ’s crucifixion is when the Son cries out: Father, why have you abandoned me? Chávez must have also felt abandoned by God. We find the sanctity of Chávez – not his divinity – in that pain.
[Brazilian theologian] Leonardo Boff once said something about Christ’s crucifixion that resonates with Chávez: theologically, it’s difficult to understand why God the Father abandons his Son, but God’s absence reminds us of our fragility and our inextricable connection to humanity.
For me, as a man of faith, Christ and Chávez have different places. Chávez was a brother in God, but Jesus is the older brother.
Chávez’s humanity was evident in his love for and his connection with the pueblo. This is captured in the iconic photo of him standing in the rain during the 2012 presidential campaign: because it wasn’t just any rain; the rain pouring down on him was the rain that blesses, cleanses, and washes away the tears of the pueblo.
Losing Chávez wasn’t easy, and I believe we’ve been slow to respond to the spiritual wake-up call that he embodied. We’ve been somewhat lethargic – not exactly delayed, but sluggish – at a time when conservatism and evangelical fundamentalism are advancing. We have been ineffective in reclaiming this spiritual and political synthesis that Chávez embodied.
As dwellers of this continent, the God of all names occupies a place in our lives and hearts. Alongside that, a passion burns in many people for justice and a commitment to the Revolution that seeks to make justice a reality. Chávez combined both.
We have centered our conversation on Chávez’s spirituality, but there are other, more playful aspects of his way of doing politics.
Chávez’s approach to spirituality was a unique synthesis. It was often playful, but always enlightening. I say this based on the diverse readings he did – both early and late in life – and his command of the biblical text. All this merged his deep understanding of Venezuelan and continental history, and his passion for Bolívar. Chávez embodied a popular, grassroots-based Latin American and Caribbean liberation theology.
But Chávez’s theology merged his innovative political vision as a leader with a discourse that brought diverse themes. These ranged from baseball tactics – Who’s got the ball? Who’s up to bat? What kind of hit will they make? – to the Alma Llanera [possibly Chávez’s favorite song], all of it combined with his rejoicing in the world of the common man and his buzzing desire to enjoy life.
Chávez’s character was something that he often backgrounded in his role as a leader, orator, public figure, and head of state. He often stood in his post with “proper” composure, but sometimes he couldn’t help himself, like the time at the UN General Assembly when he said “It smells like sulfur here,” after Bush had spoken. Chávez’s spontaneity and candor won us all over.
But Chávez was not just about baseball and singing on stage. Like Fidel, he embodied an intellectual tradition that can be traced back to thinkers like Simón Rodríguez [Bolívar’s teacher] and José Martí, whose understanding of education was revolutionary and ahead of their time. I’d say Rodríguez and Martí anticipated much of what [Brazilian educator] Paulo Freire developed in Latin America during the 1960s and 70s.
Both Fidel and Chávez addressed the real, concrete problems people face. They would take the time to analyze a problem thoroughly – its causes, consequences, and underlying priorities – before proposing solutions. For both, the central element to any solution was the subject: the masses, the pueblo.
Revolutionary transformation – the process of addressing every problem with a broader vision – cannot be conceived without popular participation and protagonism. Mobilizing the people, actively involving them, making them the protagonists of change – this was fundamental to the vision that Fidel and Chávez shared… but in Chávez, play and joy were also integral to the whole affair.
This combination resonated deeply with our pueblos. Chávez was a fusion of reflection, spirituality, and celebration, which served as both a form of resistance and a principle of hope.
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College Football Playoff championship bracket: Schedule and how to watch all CFP games – USA TODAY
After a riveting 15-week college football season filled with unforgettable moments and unexpected upsets, the highly anticipated College Football Playoff is set to commence. With 12 teams still in the running for the coveted national title, the excitement is palpable.
In the first-round of the College Football Playoff, teams seeded No. 5 through No. 12 will engage in elimination games. The action kicks off with a Friday night showdown between No. 7 Notre Dame and No. 10 Indiana. Saturday will be a day filled with three games. The winners of these matchups will earn the right to challenge one of the top four seeds in the quarterfinals.
The four top teams from the quarterfinals will progress to the pivotal semifinals, which will be held at either the Orange Bowl on January 9 or the Cotton Bowl on January 10. The outcomes of these matchups will determine the two teams that will battle for the College Football Playoff national championship on January 20 in Atlanta.
Here is the complete College Football Playoff bracket and information on how to watch your team’s journey to the national title.
More:Mike Norvell, Mike Gundy lead college football coaches paying loser’s tax amid NIL revolution
All times Eastern
FRIDAY, DEC. 20
SATURDAY, DEC. 21
The four quarterfinal games will be played on New Year’s weekend at the site of four bowl games, with one game on Dec. 31 and three on Jan. 1.
TUESDAY, DEC. 31
WEDNESDAY, JAN. 1
The semifinal games will be played Jan. 9 and Jan. 10 at the site of two bowl games.
THURSDAY, JAN. 9
FRIDAY, JAN. 10
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APPLIED THERAPEUTICS BREAKING NEWS: BFA Law Announces that – GlobeNewswire
| Source: Bleichmar Fonti & Auld
NEW YORK, Dec. 20, 2024 (GLOBE NEWSWIRE) — Leading securities law firm Bleichmar Fonti & Auld LLP announces that a lawsuit has been filed against Applied Therapeutics, Inc. (NASDAQ: APLT) and certain of the Company’s senior executives for potential violations of the federal securities laws.
If you invested in Applied Therapeutics, you are encouraged to obtain additional information by visiting https://www.bfalaw.com/cases-investigations/applied-therapeutics-inc.
Investors have until February 18, 2025, to ask the Court to be appointed to lead the case. The complaint asserts claims under Sections 10(b) and 20(a) of the Securities Exchange Act of 1934 on behalf of investors in Applied Therapeutics securities. The case is pending in the U.S. District Court for the Southern District of New York and is captioned Alexandru v. Applied Therapeutics, Inc., et al., No. 24-cv-09715.
What is the Lawsuit About?
Applied Therapeutics is a clinical-stage biopharmaceutical company specializing in the development of novel drug candidates against validated molecular targets in rare diseases. The Company’s lead drug candidate, govorestat, is a central nervous system penetrant Aldose Reductase Inhibitor for the treatment of CNS rare metabolic diseases, including Galactosemia.
During the relevant period, the Company stated that its New Drug Applications submitted to regulators for govorestat were “supported by rapid and sustained reduction in galactitol, which resulted in a meaningful benefit on clinical outcomes across pediatric patients, alongside a favorable safety profile.” Applied Therapeutics also assured investors that its tests were “performed properly” and that the Company “felt good about the quality of the data,” stating that it “took really extensive steps” and “actually videotaped” and had “master trainers” review all of the performances of the 10-meter walk-run test—the primary endpoint of the Company’s Phase III INSPIRE study for govorestat.
The Stock Declines as the Truth is Revealed
On November 27, 2024, Applied Therapeutics issued a press release stating that the FDA issued a Complete Response Letter for the NDA for govorestat. The Complete Response Letter stated that the FDA completed its review of the application and determined that it was unable to approve the NDA due to “deficiencies in the clinical application.”
This news caused the price of Applied Therapeutics stock to fall more than 80% over the course of multiple trading days, from a closing price of $10.21 per share on November 26, 2024 to a closing price of $1.75 per share on December 2, 2024.
Then, on December 2, 2024, Applied Therapeutics revealed that it received a warning letter from the FDA relating to its govorestat study discussing “issues related to electronic data capture” and “a dosing error in the dose-escalation phase of the study resulting in slightly lower levels than targeted in a limited number of patients[.]”
This news caused the price of Applied Therapeutics stock to fall more than 26% over the course of multiple trading days, from a closing price of $1.75 per share on December 2, 2024 to a closing price of $1.29 per share on December 5, 2024.
Click here for more information: https://www.bfalaw.com/cases-investigations/applied-therapeutics-inc.
What Can You Do?
If you invested in Applied Therapeutics you may have legal options and are encouraged to submit your information to the firm.
All representation is on a contingency fee basis, there is no cost to you. Shareholders are not responsible for any court costs or expenses of litigation. The firm will seek court approval for any potential fees and expenses.
Submit your information by visiting:
https://www.bfalaw.com/cases-investigations/applied-therapeutics-inc
Or contact:
Ross Shikowitz
ross@bfalaw.com
212-789-3619
Why Bleichmar Fonti & Auld LLP?
Bleichmar Fonti & Auld LLP is a leading international law firm representing plaintiffs in securities class actions and shareholder litigation. It was named among the Top 5 plaintiff law firms by ISS SCAS in 2023 and its attorneys have been named Titans of the Plaintiffs’ Bar by Law360 and SuperLawyers by Thompson Reuters. Among its recent notable successes, BFA recovered over $900 million in value from Tesla, Inc.’s Board of Directors (pending court approval), as well as $420 million from Teva Pharmaceutical Ind. Ltd.
For more information about BFA and its attorneys, please visit https://www.bfalaw.com.
https://www.bfalaw.com/cases-investigations/applied-therapeutics-inc
Attorney advertising. Past results do not guarantee future outcomes.
🏀 Basketball Legends 🏀 codes for December 2024 – VG247
Block, steal, shoot!
Basketball Legends is a popular Roblox game which offers quick-fire B Ball action. Instead of having to think about what team you want to play for, or trying to look for a lobby to join, the experience immediately drops you into a 5v5 online match with random players. You could suddenly spawn in the middle of a quarter, or right before a match starts when you need to select a captain.
Either way, it won’t be long till you’re blocking, screening and shooting hoops with other Roblox players. If you want to upgrade your character as quickly as possible, so they’re ready to step on court, you can redeem a couple of Basketball Legends codes to help you out. Codes offer freebies like coins, which are used to buy new cosmetics and emotes, as well as stat boosts which will help you progress quicker.
Here’s how you can redeem a code in Basketball Legends:
If the code you entered is active, then the text in the textbox will change to ‘Code has been redeemed’. If the code is for extra coins, you’ll also see that the coins included with the code have been added to your balance. If the code was for a stat boost instead, you’ll now see a timer on screen showing you how much longer is left for your buff.
However, if the code you entered is no longer working, then the text in the textbox will instead change to ‘Code is expired’ when you initially try to redeem it. Codes for Basketball Legends, like other Roblox games, don’t last forever so it’s best to redeem new codes as quickly as possible.
That’s it for our guide to Basketball Legends codes. If you need a hand with other popular Roblox games, check out our lists of Blade Ball codes, Blox Fruits codes, Peroxide codes, Arm Wrestle Simulator codes and Untitled Boxing Game codes.
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Herb-Drug Interactions – National Center for Complementary and Integrative Health
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NCCIH Clinical Digest
for health professionals
The possibilities of drug interactions, direct toxicities, and contamination with active pharmaceutical agents are among the safety concerns about dietary and herbal supplements. Although there is a widespread public perception that herbs and botanical products in dietary supplements are safe, research has demonstrated that these products carry the same dangers as other pharmacologically active compounds. Interactions may occur between prescription drugs, over-the-counter drugs, dietary supplements, and even small molecules in food —making it a daunting challenge to identify all interactions that are of clinical concern.
Concerns about herb-drug interactions are often not based on rigorous research. Most herb-drug interactions identified in current sources are hypothetical, inferred from animal studies or cellular assays, or based on other indirect means; however, attention to this issue is needed for drugs with a narrow therapeutic index, such as cancer chemotherapeutic agents, warfarin, and digoxin.
To date, well-designed clinical studies evaluating herbal supplement–drug interactions are limited and sometimes inconclusive. This issue of the Digest provides information about several herbs and their potential interactions with other agents.
What the Science Says:
Herb-Drug Interactions
There are uncertainties about whether ginseng might interact with certain medications, such as calcium channel blockers and other high blood pressure medications, as well as statin medications and some antidepressants. Studies on the effect of Asian ginseng on the anticoagulant warfarin have had mixed results.
Read more about the efficacy and safety profile of Asian ginseng
Cat’s claw may interact with anticoagulant/antiplatelet drugs, hypertensive drugs, calcium channel blockers, cytochrome P450 3A4 (CYP3A4) substrates, and immunosuppressants.
Read more about the efficacy and safety profile of cat's claw
Preliminary studies suggest that taking chamomile along with birth control pills might decrease the effects of oral contraceptives.
Interactions between chamomile and some drugs metabolized by the liver and warfarin have been reported, and there are theoretical reasons to suspect that chamomile might interact with other drugs as well, such as sedatives.
Read more about the efficacy and safety profile of chamomile
There is conflicting evidence about whether cranberry interacts with the anticoagulant warfarin.
Read more about the efficacy and safety profile of cranberry
Taking Ginkgo biloba with warfarin is associated with increased risk for major bleeding events compared to warfarin alone. Concomitant use of Ginkgo biloba preparations and efavirenz (a non-nucleoside reverse transcriptase inhibitor) is not recommended.
Read more about the efficacy and safety profile of ginkgo
A study funded by the National Center for Complementary and Integrative Health (NCCIH) found that levels of metformin decreased about 25 percent in healthy adults who were given goldenseal extract plus metformin. This drop was enough to potentially hinder glucose control in people with type 2 diabetes taking metformin.
Read more about the efficacy and safety profile of goldenseal
Green tea at high doses has been shown to reduce blood levels and, therefore, the effectiveness of the drug nadolol, a beta-blocker used for high blood pressure and heart problems. Green tea extract can reduce blood levels of the cholesterol-lowering drug atorvastatin. Green tea may also interact with other medicines.
Read more about the efficacy and safety profile of green tea
St. John’s wort has been found to have an overall high risk of drug interaction because it is a potent inducer of both cytochrome P-450 enzymes and intestinal P-glycoprotein.
Clinically significant interactions with St. John’s wort and the immunosuppressant drug cyclosporine, the antiretroviral agent indinavir, oral contraceptives, coumadin, digoxin, and benzodiazepines, among others, have been documented.
Read more about the efficacy and safety profile of St. John's wort
NCCIH Clinical Digest is a service of the National Center for Complementary and Integrative Health, NIH, DHHS. NCCIH Clinical Digest, a monthly e-newsletter, offers evidence-based information on complementary health approaches, including scientific literature searches, summaries of NCCIH-funded research, fact sheets for patients, and more.
The National Center for Complementary and Integrative Health is dedicated to exploring complementary health products and practices in the context of rigorous science, training complementary health researchers, and disseminating authoritative information to the public and professionals. For additional information, call NCCIH’s Clearinghouse toll-free at 1-888-644-6226, or visit the NCCIH website at nccih.nih.gov. NCCIH is 1 of 27 institutes and centers at the National Institutes of Health, the Federal focal point for medical research in the United States.
Content is in the public domain and may be reprinted, except if marked as copyrighted (©). Please credit the National Center for Complementary and Integrative Health as the source. All copyrighted material is the property of its respective owners and may not be reprinted without their permission.
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Site Last Updated: December 20, 2024
Follow NCCIH:
Contact Us
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NIH…Turning Discovery Into Health®
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OKCPS reassures commitment to equitable education, regardless of proposed citizenship rule – KOKH FOX25
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by Hadley Waldren
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OKLAHOMA CITY, OKLA (KOKH) — Oklahoma City Public Schools (OKCPS) released a statement in response to the Oklahoma State Department of Education's (OSDE) proposed proof of citizenship rule.
OKCPS stated that the district will monitor developments but will continue to follow law and board policy.
Federal law guarantees a right to public education for all children regardless of immigration status.
Dr. Jamie C. Polk, OKCPS Superintendent stated the following:
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Bednarz: Breaking down Texas schools bowl games – Laredo Morning Times
Bednarz: Breaking down Texas schools bowl games Laredo Morning Times
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